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  1. 1780
    Smallpox epidemics strike Mexico and the Great Plains
    For two years, smallpox spreads from Mexico north and throughout the Great Plains, killing many members ...
  2. 1787
    Congress can regulate trade with Indian tribes
    The Commerce Clause of the U.S. Constitution, Article 1, Section 8, permits Congress to make all laws ...
  3. 1803
    Congress orders medical care for Native peoples
    The federal government formally assigns the responsibility for providing medical care for Native peoples ...
  4. 1805
    Tenskwatawa and Tecumseh call for unity among tribes
    With the Shawnee under siege, fragmented, and dispersed, Lalawithika has a spiritual revelation that ...
  5. 1812
    Cherokee and Choctow hope for long-term U.S. alliance
    As the U.S. and Britain fight the War of 1812 on fronts from Mexico to Canada, tribes seek strategic ...
  6. 1819
    Congress pays missionaries to ‘civilize’ American Indians
    Congress appropriates $10,000 to pay what it calls people of “good moral character” to help the U.S. eliminate ...
  7. 1823
    Supreme Court rules American Indians do not own land
    The first of three court cases (the “Marshall Trilogy”) that become the foundation of American Indian ...
  8. 1824
    U.S. establishes Office of Indian Affairs in War Department
    Establishment of the Office of Indian Affairs within the War Department puts in place the bureaucracy ...
  9. 1832
    Winnebago–U.S. treaty promises doctor
    The U.S. Department of War negotiates a treaty at Rock Island, Illinois, with the Winnebago Tribe in ...