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  1. 1836
    Hawaiian monarchs order foreigners screened for smallpox
    Kuhina Nui Elizabeth Kaho‘anoku Kina‘u (a wife of the late Kamehameha II) takes the first documented ...
  2. 1863
    Leprosy spreads
    The missionary physician Dwight D. Baldwin of Lahaina on Maui reports that 54 people in his church are ...
  3. 1841
    Native Hawaiian workers mistreated on sugar plantations
    Anglo-American businessmen begin to shift the native agricultural economy to a plantation system of ...
  4. 1845–48
    A series of epidemics kills thousands in Hawai‘i
    Successive epidemics of diarrhea, influenza, measles, and whooping cough kill 10,000 in the Hawaiian ...
  5. 1847
    Pharmacies open in Hawai‘i
    In Honolulu, Dr. G. Watson and Dr. Robert Wood found three pharmacies—the first in Hawai‘i. ... Medicine ...
  6. 1848
    Successive epidemics spread across U.S., Alaska, Hawai‘i
    In September, a series of deadly epidemics, including measles, whooping cough, and influenza, sweeps ...
  7. 1848
    Hawaiian monarch divides land; paves way for foreign ownership
    King Kamehameha III institutes the Great Mahele, or land division, which destroys the ahupua‘a (the traditional ...
  8. 1850
    Kamehameha III appoints a Board of Health
    King Kamehameha III establishes Hawai‘i’s first Board of Health to organize the response to epidemics ...
  9. 1853
    Smallpox epidemic spreads to Hawai‘i
    Smallpox takes the lives of more than 5,000 Hawaiians, making it among the three worst epidemics in ...
  10. 1854
    Kamehameha IV turns to Western medicine to fight smallpox
    King Kamehameha IV orders smallpox vaccinations for all in the Kingdom of Hawai‘i. ... Epidemics ... Hawai‘i ... Watercolor ...
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