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  1. 1779
    Future Hawaiian king meets British explorer
    Kamehameha, the 25-year-old future monarch of Hawai‘i and nephew of King Kalani‘opu‘u of the Big Island ...
  2. 1804
    Epidemic strikes Kamehameha’s warriors on O‘ahu
    As King Kamehameha prepares to attack the island of Kaua‘i from his base on O‘ahu to expand his influence ...
  3. 1824–26
    Pulmonary epidemic hits Hawai‘i
    An epidemic that is suspected to be whooping cough kills thousands of Native Hawaiians. ... Whooping cough, ...
  4. 1836
    Hawaiian monarchs order foreigners screened for smallpox
    Kuhina Nui Elizabeth Kaho‘anoku Kina‘u (a wife of the late Kamehameha II) takes the first documented ...
  5. 1863
    Leprosy spreads
    The missionary physician Dwight D. Baldwin of Lahaina on Maui reports that 54 people in his church are ...
  6. 1845–48
    A series of epidemics kills thousands in Hawai‘i
    Successive epidemics of diarrhea, influenza, measles, and whooping cough kill 10,000 in the Hawaiian ...
  7. 1848
    Successive epidemics spread across U.S., Alaska, Hawai‘i
    In September, a series of deadly epidemics, including measles, whooping cough, and influenza, sweeps ...
  8. 1850
    Kamehameha III appoints a Board of Health
    King Kamehameha III establishes Hawai‘i’s first Board of Health to organize the response to epidemics ...
  9. 1853
    Smallpox epidemic spreads to Hawai‘i
    Smallpox takes the lives of more than 5,000 Hawaiians, making it among the three worst epidemics in ...
  10. 1854
    Kamehameha IV turns to Western medicine to fight smallpox
    King Kamehameha IV orders smallpox vaccinations for all in the Kingdom of Hawai‘i. ... Epidemics ... Hawai‘i ... Watercolor ...
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