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  1. 1832
    U.S. vaccinates Native peoples on the frontier against smallpox
    Congress passes the Indian Vaccination Act and appropriates $12,000 to hire physicians to vaccinate Native ...
  2. 1833
    Whooping cough crosses the Great Plains
    Whooping cough spreads across the U.S., killing babies and children, for whom the infection is particularly ...
  3. 1834
    Mexico denies return of mission lands to Chumash
    In California, the Mexican government frees the Chumash, who had been enslaved by the Spanish in California ...
  4. 1834
    Priest gains Tlingit support by offering vaccinations
    The Russian Orthodox priest, Father Veniaminov, moves from the Aleutians to Sitka. He is at first unpopular ...
  5. 1835
    Russian-American Company orders Native vaccinations
    To protect Russians from smallpox transmission from Native peoples, the Russian-American Company, which ...
  6. 1836
    Hawaiian monarchs order foreigners screened for smallpox
    Kuhina Nui Elizabeth Kaho‘anoku Kina‘u (a wife of the late Kamehameha II) takes the first documented ...
  7. 1836–39
    Unangan (Aleut) population declines further
    Smallpox, measles, chicken pox, and whooping cough epidemics reduce the Unangan (Aleut) population, which ...
  8. 1836–40
    Smallpox, whooping cough strike the Great Plains
    A smallpox epidemic spreads through Native communities in the West, killing 10,000 people in the Northern ...
  9. 1837–38
    Smallpox decimates tribes; survivors join together
    A smallpox epidemic destroys the Numakiki (Mandan) Indians in North Dakota. Although they experienced ...
  10. 1863
    Leprosy spreads
    The missionary physician Dwight D. Baldwin of Lahaina on Maui reports that 54 people in his church are ...
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